Vuity Eye Drops for Near Vision

Eye Anatomy. Image courtesy of Caitlin Albritton.

What is Vuity?

Vuity is a new eye drop to improve near vision in mature adults and is available with a prescription. It became available with FDA approval in 2021.  The generic name for Vuity is pilocarpine, a drug used for years to treat some types of glaucoma.  

How does Vuity work?

Vuity works by causing the pupil to constrict.  The pupil is the small black opening in the center of the iris (the colored part of the eye, usually blue or brown).  When the pupil constricts it provides a greater depth of field just like a camera with a small aperture.  Vuity also constricts the ciliary muscle inside the eye.  This is the muscle that normally focuses the eye from distance to near. 

What did the studies of Vuity show?

Gemini I and II were studies to prove the benefit of Vuity.  Between the two studies a total of 375 patients were treated.  One hour after instilling Vuity, about 26% more patients on Vuity had an improvement in near vision (three lines on the eye chart) compared with patients given a placebo.  This suggests that a majority of patients may experience less of an effect.  Vuity likely provides a modest short-term effect with minimal risk to most people making it of marginal value (cost/benefit ratio).     

How do you use Vuity?

Apply a drop of Vuity to each eye in the morning. The drop takes affect within an hour and slowly loses its effect over 6-10 hours. If Vuity is used more than once a day, it is more likely to cause side effects.   

What are the adverse effects of Vuity?

Vuity should not be used by anyone with an allergy to pilocarpine.  It should also be avoided in people prone to iritis.  Some patients notice poor vision at night while using Vuity; this is especially true if it is used after noon or in eyes with cataract.  Therefore, caution may be needed while driving at night.  Sometimes, patients experience accommodative spasm in which they have trouble focusing from near to distance.  A brow ache may occur when the drop is started, but usually subsides over time with continued use of Vuity.  Little is known about the safety of Vuity in pregnancy and during breast feeding.  If you use soft contact lenses, they should be removed before instilling Vuity.  They may be placed back in the eye after 10 minutes.  Use Vuity at least 5 minutes apart from other eye drops you use for other conditions.  Very rare adverse effects from Vuity may include acute angle-closure glaucoma and retinal detachment.  Therefore, the following symptoms should be reported promptly: new flashes and/or floaters, any loss of vision (including loss of side vision), pain, or significant redness.  

By Scott E Pautler, MD

For a telemedicine consultation with Dr Pautler, please send email request to spautler@rvaf.com. We accept Medicare and most insurances in Florida. Please include contact information (including phone number) in the email. We are unable to provide consultation for those living outside the state of Florida with the exception of limited one-time consultations with residents of the following states: Alabama, Arkansas, Connecticut, Georgia, Minnesota, and Washington.

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